Related documentation
Advanced algorithm documentation
Ion Reporter™ Software contains many advanced algorithms that have been optimized specifically for Ion Torrent™ semiconductor Sequencing technology. Below are application notes and white papers that provide more background and are available at the Thermo Fisher Scientific website.
Variant filtering and prioritization using the Ion AmpliSeq™ Exome trio workflow in Ion Reporter™ Software, available at http://tools.thermofisher.com/content/sfs/brochures/Ion-AmpliSeq-Exome-Application-Note.pdf
Metagenomics 16S Algorithm Overview, available at http://tools.thermofisher.com/content/sfs/brochures/ion-reporter-16s-metagenomics-algorithms-whitepaper.pdf.
Application Note: CNV detection by Ion semiconductor sequencing, available at http://tools.thermofisher.com/content/sfs/brochures/CNV-Detection-by-Ion.pdf.
Application Note: Detection of aneuploidy in a single cell using the Ion ReproSeq PGS Kit, available at https://tools.thermofisher.com/CONTENT/SFS/BROCHURES/ANEUPLOIDY-APP-NOTE.PDF.
Cancer genomics and transcriptomics research, available at https://www.thermofisher.com/us/en/home/global/forms/life-science/request-NGS-application-note.html?appnote=5.
Low-frequency mutations from cell-free DNA, available at http://tools.thermofisher.com/content/sfs/brochures/ngs-analysis-mutations-cfdna-app-note.pdf.
Reproductive genomics and inherited disease research, available at http://tools.thermofisher.com/content/sfs/brochures/Ion-S5-S5XL-App-Note-Inherited-Disease.pdf.
Rapid sequencing of microorganisms, available at http://tools.thermofisher.com/content/sfs/brochures/Ion-S5-S5XL-App-Note-Infectious-Disease.pdf.