Apply a sequence variant baseline workflow preset to an analysis workflow

You can create a custom Sequence Variant Baseline workflow preset that you can use as a baseline control to detect somatic variants. For more information, see Sequence variant baselines. You must add the custom baseline to an analysis workflow to use the baseline in an analysis.

  1. In the Workflows tab, start to create or copy an analysis workflow.
    • Click Overview, then select an analysis workflow to copy, then click Actions > Copy .

    • Click Create Workflow.

  2. In the Reference workflow bar step, select the target regions file for the panel that is associated with the analysis workflow.
  3. In the Parameters workflow bar step, click the link to open the Variant Finding parameters and click Advanced.
  4. Scroll to select a sequence variant baseline that matches the panel associated with the analysis workflow from the Analysis SVB File dropdown list.

    After you make a selection, you can view details for the baseline in the Summary pane.

  5. Click Next.
  6. Proceed through the remaining steps in the workflow bar.

    For more information, see Steps in analysis workflow creation.

  7. In the Confirm step, click Save Workflow.