You can edit a MyVariants database in Ion Reporter™ Software.
IMPORTANT! Edits to MyVariants can affect the MyVariants settings that are made by
other members of the organization if you are sharing a MyVariants database.
You can change the Important
or Ignore flags
that are associated with variants in a MyVariants database.
If you delete an analysis that includes a variant that is labeled as Important or Ignore, the MyVariants database is unaffected and the variant flags, notes, and classifications remain.
You can also add notes to variants in a MyVariants database.
In the
Analyses tab,
click
MyVariants.
In the
MyVariants
table, select a specific MyVariants database from the list.
Review the flags, notes and classifications for each variant, then update each
of the options, if needed.
In the
(Flag)
column, expand
(Flag list),
then select the appropriate flag.
Table 1.
Option
Description
Important
The flag icon becomes orange in the row of the
variant and the variant is added to the MyVariants
database.
Important is used
to track variants that are relevant to the
research.
Ignore
The flag icon becomes gray in the row of the variant and the variant is added to the
MyVariants database.
Ignore
is often used to denote known false positives or
false negatives, or variants that are not
associated with the research area.
None
All variants are marked None
by default. Select None to
remove an Important or
Ignore flag and to remove a
variant from the MyVariants database.
In the
(Note)
column, click
(Add)
, click the Notes tab, then enter a note for the
variant. When you are finished, click
Add Note
In the Classification column, you can select one of
the following classifications for each variant of interest:
Unclassified, Unknown, Benign, Suspected Benign, Likely Benign,
Deleterious, Suspected Deleterious, Pathogenic, Likely Pathogenic, VUS,
Uncertain Significance, Technical Artifact.
(Flag)
column, expand
(Flag list),
then select the appropriate flag.
(Note)
column, click
(Add)
, click the Notes tab, then enter a note for the
variant. When you are finished, click
Add Note
