Example sample coverage plot for a single analysis positive for a fusion imbalance in NTRK1

RNA Exon Tile Fusion Imbalance plots provide a visual representation of the RNA fusion imbalance analysis results for the detection of novel fusions in a partner agnostic manner. Sample Coverage for Imbalance Analysis plots show the expression profile for each exon‑exon tiling amplicon for each gene.

The blue line indicates the expression level across NTRK1 and indicates a significant imbalance in this example. The collection of fusion-negative samples is used to construct the baseline and each fusion-negative sample is represented by a grey line in the plot. The distinction between NTRK1 and the baseline shows a significant difference with a p-value of 0.0019. The location of the predicted breakpoint is denoted with the dashed red line.