Transcripts in REFSEQ and ENSEMBL canonical transcripts file
In UCSC curated canonical transcripts set, there are some discrepancies when multiple transcripts are used for a given gene. The shorter transcripts have been removed and the transcript with the appris_principal_1 tag is retained in the Ion Reporter™ Software REFSEQ canonical transcript set. This tag is used by gencode to mark the primary transcript of a specific gene. If the appris_principal_1 tag is missing, the longest transcript is used so that there is just one canonical transcript for a given gene. If two transcripts are the same length, Ion Reporter™ Software includes both genes and lists them in alphabetical order.
The UCSC transcripts for the following genes are replaced with the transcripts in the New transcript column in Ion Reporter™ Software:
|
Gene |
Current transcript |
New transcript |
|---|---|---|
|
FGFR2 |
NM_022970.3 |
NM_000141.5 |
|
FGFR3 |
NM_001163213.1 |
NM_000142.5 |
|
ABL1 |
NM_007313.2 |
NM_005157.6 |
|
ARAF |
NM_001256196.1 |
NM_001654.5 |
|
CHEK2 |
NM_001005735.1 |
NM_007194.4 |
|
GNAS |
NM_080425.2 |
NM_000516.7 |
|
TP53 |
NM_001276760.1 |
NM_000546.6 |
