Edit a MyVariants database

You can edit a MyVariants database in Ion Reporter™ Software.

You can change the Important or Ignore flags that are associated with variants in a MyVariants database.

If you delete an analysis that includes a variant that is labeled as Important or Ignore, the MyVariants database is unaffected and the variant flags, notes, and classifications remain.

You can also add notes to variants in a MyVariants database.

  1. In the Analyses tab, click MyVariants.
  2. In the MyVariants table, select a specific MyVariants database from the list.
  3. Review the flags, notes and classifications for each variant, then update each option, if needed.
    1. In the  (Flag) column, expand (Flag list), then select the appropriate flag.
      Table 1.

      Option

      Description

      Important

      		 The flag icon becomes orange in the row of the variant and the variant is added to the MyVariants database.

      Important is used to track variants that are relevant to the research.

      Ignore

      The flag icon becomes gray in the row of the variant and the variant is added to the MyVariants database. Ignore is often used to indicate known false positives or false negatives, or variants that are not associated with the research area.

      None

      All variants are marked None by default. Select None to remove an Important or Ignore flag and to remove a variant from the MyVariants database.
    2. In the  (Note) column, click  (Add) , click the Notes tab, then enter a note for the variant. When done, click Add Note
    3. In the Classification column, you can select from the following classifications for each variant of interest.

      • Unclassified

      • Unknown

      • Benign

      • Suspected Benign

      • Likely Benign

      • Deleterious

      • Suspected Deleterious

      • Pathogenic

      • Likely Pathogenic

      • VUS (Variant of Unknown Significance)

      • Uncertain Significance

      • Technical Artifact