Compare the immune repertoire between samples

Ion Reporter™ Software can perform multisample (or cross‑sample) analysis to compare the immune repertoire between samples.

Under the Analyses tab, in the Overview screen, select the appropriate analysis workflow from the Workflow filter.
Select the adjacent checkboxes to select 2 or more results files from the available list of analyses, then click Visualize to generate a clone summary table.

Select samples for a multisample analysis to generate comparison plots.

Option	Description
Select 2 samples, then click Compare Samples.	An interactive scatter plot for the selected samples is shown in the Comparison Plots tab.
Select 2 or more samples, then click Compare Samples.	A Jaccard Similarity Index for the selected samples is shown in the Comparison Plots tab.

The visualized multisample analysis results are reported side-by-side in a clone summary table in rank order from most frequent to least frequent. For more information, see Clone Summary table.

You can also download the multisample clone summary table or the multisample metrics file. For more information, see Download clone summary and lineage summary files.
The interactive scatter plot indicates the frequency of clones across 2 samples. For more information, see Example correlation and proportion of shared clones.
The Jaccard similarity index is determined for each pairwise comparison and is displayed in heat map form. For more information, see Example Jaccard Similarity Index for selected samples.