Variant Effect filter

This filter can be added to filter chains in the software to detect the effect of variants on coding sequences. Specific values include:

• refAllele

• unknown

• synonymous

• missense

• nonframeshiftInsertion

• nonframeshiftDeletion

• nonframshiftBlockSubstitution

• nonsense

• stoploss

• frameshiftInsertion

• frameshiftDeletion

• frameshiftBlockSubstitution

Filter conditions include the ability to select all (Filter Option set to In), none (Filter Option set to Not In), or to select specific values, and to include or exclude unannotated variants in filtered analysis results.

The filter returns variants in samples that match the selected variant effects.