Select SHM profile from the
Views list to
see a histogram that represents the data. Immune repertoire analysis results report
the frequency of somatic hypermutation (SHM) over the variable gene portion of each
clone of a given isotype. This view is available only for the Oncomine™ BCR IGH‑LR Assay and Oncomine™ BCR IGH‑SR Assay.
SHM is calculated by determining the number of mismatches between a clone variable gene sequence and the best matching IMGT® variable gene allele.
Variable gene somatic hypermutation (SHM) by isotype
Click the isotype above the SHM profile plot to further partition the data by isotype.
