View Genomic Instability Metric (GIM) in analysis results
Some Oncomine™ assays used with Ion Reporter™ Software show a metric for genomic instability. The Genomic Instability Metric (GIM) is a proprietary measurement that quantifies genomic scarring associated with Homologous Recombination Deficiency (HRD). It summarizes unbalanced copy number changes in autosomes that are determined using genomic segmentation, and generates a value between 0-100. Higher GIM values correlate with the observation of more genomic instability in the sample.
In the Analyses tab, click Overview.
Search, sort, or filter the Analyses table to find the sample result of interest.
In the Analysis column, click the hyperlink for the analysis of interest to open Analysis Results screen.
Figure 1. Example analysis results with a low Genomic Instability Metric
Figure 2. Example of analysis results with a high Genomic Instability Metric.
The Genomic Instability Metric is listed at the top of the Analysis Results screen. Based on a predefined threshold, a Genomic Instability Status of High or Low is shown.
