InconsistentWithParents

A proband variant is consistent with its parents if one of its alleles is present in the genotype of the father at this variant position and its other allele is present in the genotype of the mother at this variant position.

A proband variant is assigned the category InconsistentWithParents if all of the following are true:

  • The variant has coverage of at least consistencyMinCoverage.

  • The father's genotype has coverage of at least consistencyMinCoverage at this variant position.

  • The mother's genotype has coverage of at least consistencyMinCoverage at this variant position.

  • The variant is not consistent with variants of parents.