This filter can be added to filter chains in the software to evaluate the impact of variants
observed in samples that match those in the National Center for Biotechnology
Information (NCBI) ClinVar database. The specific databases are:
Clinvar(20180725)
Clinvar(20190909)
The impact values that can be included in the filter chain are: Pathogenic, Likely benign, Benign, other, Likely pathogenic, Uncertain significance, not provided, and drug response.
The filter returns all variants with the selected impact values that match those in the NCBI ClinVar database.