Example time series graphs

Time series line graphs show quantitative variant changes, such as the allele frequency, over time. In the software, you can generate a single time series graph or you can simultaneously generate multiple graphs with different types of variants, such as both SNVs and Fusions graphs. In this example, all three variant graphs are shown. The SNV/Indel graph shows the allele ratio of c743G>A TP53 mutations over the course of 15 months. The CNV graph shows the CNV ratio of FGFR3 and MET and the Fusions graph shows read counts per million for MET over 15 months.

The following Variant Label preferences were set for this example.

Type of chart	Variant Label choice	Example shown
SNV/Indel	Gene + Coding	TP53 c743G>A
CNV	Genes	FGR3 MET
Fusions	Genes	MET Note: In this example only one gene is shown because an RNAExonVariant is selected.

Click Show All, SNV / Indel, CNV, or Fusion to view all graphs or limit the view to the selected graph.
Click Selected Analyses to view the list of the analyses that were selected.
A general key for graphs. Variant calls are represented by an open circle, hotspot reference alleles are represented by a filled square, and data points with no call are represented by a filled triangle.
Click Download to download a ZIP file that contains PNG files of the graph or graphs.
Apply Preferences to customize the graphs. For more information, see Create and view a time series graph.
The type of variant graph: SNV / Indel, CNV, or Fusion.
A key for each graph that can be customized. Click a variant label in the key to remove all data points for that variant label from the graph.
Hover the mouse over a data point to view the data.
In this example, a no call data point is shown in the second position of the SNV/Indel Time Series line graph.
In this example, a reference call data point is shown in the third position of the SNV/Indel Time Series line graph.

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Example time series graphs