Example plot for RET driver gene

This example plot for the RET driver gene shows the correlation between low imbalance values and samples that do not contain a fusion (in red). Samples that contain a fusion (in blue) all contain higher imbalance values. For more information on novel fusion detection in Ion Reporter™ Software, see Novel fusion detection using expression imbalance.

Zoomed in view:

• A 3'/5' Imbalance value of 0.045 or greater indicates the likely presence of a RET fusion.

  

• With a 3'/5' Imbalance value of 0.03, there is no evidence that a RET fusion is present.

• The range of 3'/5' Imbalance values between 0.045 and 0.03 is an area of uncertainty where there is some evidence that a fusion may be present. The higher the imbalance values, the more evidence there is that a RET fusion is present.