Named Variants filter

This filter can be added to filter chains in the software to detect known variants in the Ion AmpliSeq™ Community Panel for the cystic fibrosis transmembrane regulator (CFTR) gene, for example: c.2054delA.

Filter conditions include the ability to select all named variants, to select specific named variants, and to include or exclude unannotated variants in filtered analysis results.

The filter returns variants in samples that match the CFTR variants that are specified in the filter.

IMPORTANT! The Named Variants filter option is not shown in the dropdown list when you create a filter chain. To create a filter chain that uses the Named Variants filter, you need to first select an annotation set that includes the Named Variants annotation source. After you select the annotation set, the Named Variants option is shown. To determine if the annotation set contains the Named Variants annotation source, you can view the details for the annotation set in the Workflow Presets screen. For more information, see View custom annotation sources.